I have an old house wherein the electrical wring was put in incorrectly (I have had it fixed). My living room and two bedrooms face the patio. All three rooms have sliding glass doors and separate electrical switches to control the outdoor/patio lighting.
When a switch is thrown to light the patio, from the bedroom, I should be able to control the other two switches (and the outdoor lights, of course) when turning them ON and OFF.
However, I had a nasty guest stay with me and the switches have never worked the same since— his name: Mr. CIDP— the bastard!
So now when I turn the switch off in the bedroom, or in the other rooms, that switch becomes the sole controlling switch, overriding the other two. Consequently, my electric bill goes up, and that hurts! I fall over and need a cane from the shock of it!!! (Maui has the highest electric rates in USA!!!).
However, I am able to call in the electrician, Mr. PRISTINE IGG, who is able to adjust the switching so OFF means OFF, and ON means ON, no matter which switch is used. And then, Mr. T-Celly hesitates to rob me of my precious myelin and axion collections in the middle of the night when the lights can automatically go on; detect and thwart his insidious movements outside in the dark and stormy night!
If you look at IgG in an electron microscope image it is actually shaped like a " Y ". The switch I'm referring to is on the bottom right side of the " Y ". It exist on the light-chain portion that makes up the Ig antibody, it is called, FcγRIIB. How complex is it... there are four types of IgG: IgG1, IgG2, IgG3 and IgG4. So the ON/OFF switching gets complex and Mr. T Celly gets all huffy and inflamed from doing all the Boolean math, starts arguing with Mack Rofage, Den Drite and a furious Aunt Bee Celly. They just don't know when to stop arguing and inflaming each other. Yes, it is Aunt Bee Celly's relative, "Mr. Killer T. Celly" doing all the damage!!! Angry, unruly teenagers!
Call the bio-electrician, call MR. PRISTINE IGG! Or his cousin, Court A. Zone or Plasma Farr Reaches
I created this nano-scale soap opera from this link:
But the question remains, why do these receptors stop working?
I've discovered that when my IvIG works I smile and life is a whole lot better! But still... that God d***ed relapse could be waiting for me at the dawn of my new day!